Lesson 5 (a): Virus Internalization (Phagocytosis)

 


  • Phagocytosis (cell eating) – occurs in specialized mammalian cells (so-called professional phagocytes, e.g., dendritic cells and macrophages) that engulf large and essential particles.
  • Viral entry by this pathway typically involves the formation of large extracellular projections, and the internalized virus is taken into a phagosome.
  • Actin and RhoA are typically necessary for this process.


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